- Antiulcer Agents: From Plant Extracts to Phytochemicals in Healing Promotion.
Antiulcer Agents: From Plant Extracts to Phytochemicals in Healing Promotion.
Molecules (Basel, Switzerland) (2018-07-19)
Mehdi Sharifi-Rad, Patrick Valere Tsouh Fokou, Farukh Sharopov, Miquel Martorell, Adedayo Oluwaseun Ademiluyi, Jovana Rajkovic, Bahare Salehi, Natália Martins, Marcello Iriti, Javad Sharifi-Rad
PMID30018251
ABSTRACT
In this narrative review, we have comprehensively reviewed the plant sources used as antiulcer agents. From traditional uses as herbal remedies, we have moved on to preclinical evidence, critically discussing the in vitro and in vivo studies focusing on plant extracts and even isolated phytochemicals with antiulcerogenic potential. A particular emphasis was also paid to Helicobacter pylori activity, with emphasis on involved mechanisms of action. Lastly, the issue of safety profile of these plant products has also been addressed.
MATERIALS