Filtration for Bioprocessing

There are multiple options for buffer filtration in biomanufacturing. Filter selection is based on process biosafety needs, buffer throughput and economics. Filters for processing buffers in biomanufacturing provide bioburden control, sterilizing-grade or virus retention performance.

Our flexible hardware and systems for disposable depth filters are ideal for clarification at pilot and process scales, featuring the modular Pod device that enables scale-up and scale-down within the same footprint.

Pre-configured to meet all your biopharmaceutical process and filtration needs, our Series 4000™ line of single-round stainless steel filter housings offers a variety of T-Line and In-Line designs, as well as a wide range of tube sizes.

Cost-effective filtration for particulate reduction and bioburden control is vital in food and beverage production. Learn how filters can be easily integrated into your process to meet regulatory requirements and to yield high quality without compromising flavor, consistency, and safety.

Pre-sterilized, single-use filling systems offer speed and flexibility for critical final filtration and final fill operations. Learn how advances in aseptic filtration simplify PUPSIT and enable optimized sterile fill finish operations.

Gas vents and vent filters used throughout biomanufacturing help maintain near-ambient pressure in product tanks, bioreactors, closed systems, and/or related utilities. Find the right sterile vent filter for your process application needs. 

For non-destructive filter integrity testing that is fast, reliable, and repeatable, the Integritest^® 5 automated test instrument allows bubble point and diffusion testing inline or offline, with additional capability for hydrophobic filter testing when paired with the Exact-Air™ II water-based test unit.

Cell culture media filtration prevents bioreactor contamination. Selection of a sterilizing filter, mycoplasma filter, or virus filter depends on process risk.  Learn how to select the best filter for your cell culture media filtration.

Prefilters are used to remove particulates and protect downstream unit operations. They can be used to provide column protection or in front of a sterilizing-grade filter to improve capacity. Learn how our cost-effective prefilters can enhance your process economics.

Sterile filtration with disposable filters is a common operation in bioprocessing and part of every bioburden control strategy. Sterile filtration assures microbial safety of the drug for patients. Learn how to select the best sterilizing filter for your process step.

Viral safety is a key component of drug safety for patients. Virus filtration of cell culture media minimizes the risk of bioreactor contamination, while downstream virus filtration assures viral clearance. Learn how virus filtration reduces risk and enhances viral safety.

Flexible, easy-to-use filter holders are a key component for integration of the Viresolve^® Pro Solution, enabling scalable virus filtration that meets your manufacturing demands.