GW20079F
Anti-Vitamin D-Binding Protein antibody produced in chicken
affinity isolated antibody, buffered aqueous solution
Synonym(s):
Anti-VDBP
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
Recommended Products
biological source
chicken
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
human
technique(s)
indirect ELISA: suitable
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... GC(2638)
Immunogen
Immunogen Sequence: GI # 32483410, sequence 1-474
Vitamin D-binding protein (native protein).
Application
Anti-Vitamin D-Binding Protein antibody produced in chicken is suitable for indirect ELISA and western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.
Biochem/physiol Actions
Vitamin D-binding protein (also known as gc-globulin) is a protein encoded by the GC gene in humans. It transports vitamin D metabolites in the circulation. Both vitamin D metabolites and vitamin D binding proteins (VDBP) are associated with asthma (regulation in the lung during acute allergen-induced airway inflammation). Vitamin D-binding protein (VDBP) haplotypes also influence free vitamin D levels.
Physical form
Solution in phosphate buffered saline containing 0.02% sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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Aledie Navas-Nazario et al.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 112(6), 519-524 (2014-04-22)
Potential vitamin D-related influences on inflammatory diseases such as asthma are controversial, including the suggestion that vitamin D insufficiency is associated with increased asthma morbidity. Vitamin D-binding protein transports vitamin D metabolites in the circulation. Single nucleotide polymorphisms in the
A G Randolph et al.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 44(2), 231-237 (2014-01-23)
Between 75 000 and 125 000 U.S. infants are hospitalized for respiratory syncytial virus (RSV) bronchiolitis every year. Up to half will be diagnosed with asthma in later childhood. Vitamin D deficiency has been associated with susceptibility to asthma and respiratory infections.
K Bratke et al.
Clinical and experimental immunology, 177(1), 366-372 (2014-04-16)
Allergic asthma is a chronic disease of the airways associated with airway hyperresponsiveness, a variable degree of airflow obstruction, airway remodelling and a characteristic airway inflammation. Factors of the vitamin D axis, which include vitamin D metabolites and vitamin D
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