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Merck

TCF4

transcription factor 4

Synonyms:
E2-2, ITF-2, ITF2, PTHS, SEF-2, SEF2, SEF2-1, SEF2-1A, SEF2-1B, TCF-4, bHLHb19
Species:
UniProtKB ID:
Gene ID:
  • Human(6925) Summary: This gene encodes transcription factor 4, a basic helix-loop-helix transcription factor. The encoded protein recognizes an Ephrussi-box ('E-box') binding site ('CANNTG') - a motif first identified in immunoglobulin enhancers. This gene is broadly expressed, and may play an important role in nervous system development. Defects in this gene are a cause of Pitt-Hopkins syndrome. Multiple alternatively spliced transcript variants that encode different proteins have been described. [provided by RefSeq, Aug 2011]
  • Mouse(21413) transcription factor 4
  • Rat(84382) transcription factor 4
  • Zebrafish(100526651) transcription factor 4
  • domestic cat(101097354) transcription factor 4
  • dog(403949) transcription factor 4
  • cow(534935) transcription factor 4
  • sheep(101120538) transcription factor 4
  • naked mole-rat(101707519) transcription factor 4
  • domestic guinea pig(100732402) transcription factor 4

Custom & Knockdown Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-TCF4 antibody produced in mouse, clone 1F6, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Monoclonal Anti-TCF4 antibody produced in mouse, clone 1G4, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence

western blot
Anti-TCF4, C-Terminal antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
Anti-TCF4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-TCF4 (AB2) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
horse, human, mouse, pig, rat
Application
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human TCF4,
Species
human
MISSION® esiRNA, targeting mouse Tcf4,
Species
mouse