POLR2A
polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
Synonyms:
POLR2, POLRA, RPB1, RPBh1, RPO2, RPOL2, RpIILS, hRPB220, hsRPB1
Species:
Human POLR2A (5430), Mouse Polr2a (20020), Rat Polr2a (363633), domestic guinea pig Polr2a (100734232), naked mole-rat Polr2a (101725588), cow POLR2A (282312), sheep POLR2A (100144762), Zebrafish polr2a (553347), dog POLR2A (479483), domestic cat POLR2A (101098500)
UniProtKB ID:
Gene ID:
- Human(5430) Summary: This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA. [provided by RefSeq, Jul 2008]
- Mouse(20020) polymerase (RNA) II (DNA directed) polypeptide A
- Rat(363633) polymerase (RNA) II (DNA directed) polypeptide A
- domestic guinea pig(100734232) polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
- naked mole-rat(101725588) polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
- cow(282312) polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
- sheep(100144762) polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
- Zebrafish(553347) polymerase (RNA) II (DNA directed) polypeptide A
- dog(479483) polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
- domestic cat(101098500) polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-POLR2A, (N-terminal) antibody produced in mouse, clone IF17, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-phospho-RNAPII Antibody (Thr4), clone 1G7, clone 1G7, from rat,
Species Reactivity
human, mouse, yeast
Application
ChIP
immunocytochemistry
immunoprecipitation (IP)
western blot
immunocytochemistry
immunoprecipitation (IP)
western blot
Anti-phospho RNA Pol II (Ser7), clone 3D4A12 Antibody, clone 3D4A12, 1 mg/mL, from rat,
Species Reactivity
canine, human, monkey, mouse, rat
Application
ChIP
ELISA
immunocytochemistry
western blot
ELISA
immunocytochemistry
western blot
Anti-POLR2A Antibody, clone 1F5, clone 1F5, from rat,
Species Reactivity
human
Application
ChIP
immunocytochemistry
western blot
immunocytochemistry
western blot
Anti-Phospho-POLR2A-S7 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
western blot