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Merck

HTR3D

5-hydroxytryptamine (serotonin) receptor 3D, ionotropic

Synonyms:
5HT3D
Species:
UniProtKB ID:
Gene ID:
  • Human(200909) Summary: The protein encoded this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit D of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a mitogen and a hormone. This hormone has been linked to neuropsychiatric disorders, including anxiety, depression, and migraine. Serotonin receptors causes fast and depolarizing responses in neurons following activation. The genes encoding subunits C, D and E of this type 3 receptor form a cluster on chromosome 3. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2009]
  • domestic cat(101090286) 5-hydroxytryptamine (serotonin) receptor 3D, ionotropic

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Small Molecule - Agonist

Product Number
Description
Species
SR 57227A, solid,
Species
human
Metoclopramide hydrochloride, solid,
Species
human
Tropisetron monohydrochloride, solid, ≥98% (HPLC),
Species
rat, human
Quipazine maleate salt, ,
Species
human

Small Molecule - Allosteric Modulator

Product Number
Description
Species
DCEBIO, ≥98% (HPLC), solid,
Species
human

Small Molecule - Antagonist

Product Number
Description
Species
Metoclopramide hydrochloride, solid,
Species
human
Tropisetron monohydrochloride, solid, ≥98% (HPLC),
Species
rat, human
Amisulpride for system suitability, European Pharmacopoeia (EP) Reference Standard,
Species
human
Amisulpride for system suitability, British Pharmacopoeia (BP) Reference Standard,
Species
human
Amisulpride, European Pharmacopoeia (EP) Reference Standard,
Species
human

Small Molecule - Blocker

Product Number
Description
Species
Zimelidine dihydrochloride, solid,
Species
human
Trimipramine maleate salt, ≥98% (TLC), powder,
Species
human

Small Molecule - Inhibitor

Product Number
Description
Species
R-(−)-Fluoxetine hydrochloride, >98% (HPLC), solid,
Species
human
S-(+)-Fluoxetine hydrochloride, ≥98% (HPLC), solid,
Species
human
Clomipramine hydrochloride, ≥98% (HPLC), powder,
Species
human
Reserpine, ,
Species
human
Fluoxetine hydrochloride, solid,
Species
human

Small Molecule - Ligand

Product Number
Description
Species
Nω-Methyl-5-hydroxy­trypt­amine oxalate salt, ≥90% (HPLC),
Species
human

Small Molecule - Metabolite

Product Number
Description
Species
5-Hydroxyindole-3-acetic acid, ≥98% (HPLC), crystalline,
Species
human

Small Molecule - Precursor

Product Number
Description
Species
5-Hydroxy-L-tryptophan, powder,
Species
human