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Merck

HIST3H3

histone cluster 3, H3

Synonyms:
H3.4, H3/g, H3FT, H3t
Species:
Human HIST3H3 (8290), Rat Hist3h3 (287352), dog HIST3H3 (480760)
UniProtKB ID:
Q16695, B2R5K3, Q6FGU4
Gene ID:
  • Human(8290) Summary: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq, Jul 2008]
  • Rat(287352) histone cluster 3, H3
  • dog(480760) histone cluster 3, H3

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Antibodies

Product Number
Description
Species Reactivity
Application
ABE2605
Anti-H3K4me3Q5histaminyl, ,
Species Reactivity
human
Application
dot blot
western blot
ABE2578
Anti-H3Q5histaminyl, ,
Species Reactivity
bovine, human, monkey
Application
dot blot
western blot
ZRB1836
Anti-Histone H3-Lys9me2 Antibody, clone 2J13 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, rat
Application
immunocytochemistry
immunohistochemistry
inhibition assay
western blot
ZRB1888
Anti-Histone H3-Lys9me3 Antibody, clone 4J8 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, mouse, rat
Application
affinity binding assay
immunohistochemistry
inhibition assay
western blot
SAB4200485
Anti-acetyl-Histone H3 (Ac-Lys27) antibody produced in rabbit, ~1.0 mg/mL, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
immunohistochemistry
western blot

Proteins

Product Number
Description
Species
SRP0408
Histone Octamer full length human, recombinant, expressed in E. coli, ≥90% (SDS-PAGE),
Species
human