DNASE2B
deoxyribonuclease II beta
DLAD
Human DNASE2B (58511), Mouse Dnase2b (56629), Rat Dnase2b (59296), sheep DNASE2B (101110100), domestic guinea pig Dnase2b (100732795), naked mole-rat Dnase2b (101719320), chicken DNASE2B (424540), domestic cat DNASE2B (101097005), cow DNASE2B (525117), Horse DNASE2B (100064895)
- Human(58511) Summary: The protein encoded by this gene shares considerable sequence similarity to, and is structurally related to DNase II. The latter is a well characterized endonuclease that catalyzes DNA hydrolysis in the absence of divalent cations at acidic pH. Unlike DNase II which is ubiquitously expressed, expression of this gene product is restricted to the salivary gland and lungs. The gene has been localized to chromosome 1p22.3 adjacent (and in opposite orientation) to the uricase pseudogene. Two transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
- Mouse(56629) deoxyribonuclease II beta
- Rat(59296) deoxyribonuclease II beta
- sheep(101110100) deoxyribonuclease II beta
- domestic guinea pig(100732795) deoxyribonuclease II beta
- naked mole-rat(101719320) deoxyribonuclease II beta
- chicken(424540) deoxyribonuclease II beta
- domestic cat(101097005) deoxyribonuclease II beta
- cow(525117) deoxyribonuclease II beta
- Horse(100064895) deoxyribonuclease II beta
- dog(479973) deoxyribonuclease II beta
Custom & Knockdown Gene Products
siRNA
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shRNA
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Custom Gene Products
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Antibodies
Anti-DNASE2B (ab2) antibody produced in rabbit, affinity isolated antibody,
guinea pig, human, rat
western blot
Anti-DNASE2B antibody produced in rabbit, IgG fraction of antiserum,
bovine, guinea pig, horse, human, rat
western blot