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Merck

BCL10

B-cell CLL/lymphoma 10

Synonyms:
CARMEN, CIPER, CLAP, c-E10, mE10
Species:
UniProtKB ID:
Gene ID:
  • Human(8915) Summary: This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy. [provided by RefSeq, Jul 2008]
  • Mouse(12042) B cell leukemia/lymphoma 10
  • Rat(83477) B-cell CLL/lymphoma 10
  • chicken(424528) B-cell CLL/lymphoma 10
  • cow(540824) B-cell CLL/lymphoma 10
  • domestic cat(101099570) B-cell CLL/lymphoma 10
  • dog(490183) B-cell CLL/lymphoma 10
  • sheep(101113372) B-cell CLL/lymphoma 10
  • naked mole-rat(101712563) B-cell CLL/lymphoma 10
  • domestic guinea pig(100729772) B-cell CLL/lymphoma 10

Custom & Knockdown Gene Products

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-BCL10 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-Bcl-10 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
immunocytochemistry

western blot
Anti-BCL10 antibody produced in rabbit, ,
Species Reactivity
human
Application
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human BCL10,
Species
human
MISSION® esiRNA, targeting mouse Bcl10,
Species
mouse