AGTR1
angiotensin II receptor, type 1
Synonyms:
AG2S, AGTR1A, AGTR1B, AT1, AT1AR, AT1B, AT1BR, AT1R, AT2R1, AT2R1A, AT2R1B, HAT1R
Species:
Human AGTR1 (185), naked mole-rat Agtr1 (101714068), domestic guinea pig Agtr1 (100192325), sheep AGTR1 (443107), Domestic Rabbit AGTR1 (100009164), chicken AGTR1 (396065), domestic cat AGTR1 (101082936), dog AGTR1 (403836), cow AGTR1 (281607)
UniProtKB ID:
Gene ID:
- Human(185) Summary: Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. Multiple alternatively spliced transcript variants have been reported for this gene. [provided by RefSeq, Jul 2012]
- naked mole-rat(101714068) angiotensin II receptor, type 1
- domestic guinea pig(100192325) angiotensin II receptor, type 1
- sheep(443107) angiotensin II receptor, type 1
- Domestic Rabbit(100009164) angiotensin II receptor, type 1
- chicken(396065) angiotensin II receptor, type 1
- domestic cat(101082936) angiotensin II receptor, type 1
- dog(403836) angiotensin II receptor, type 1
- cow(281607) angiotensin II receptor, type 1
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Small Molecule - Agonist
Small Molecule - Antagonist
Product Number
Description
Species
Losartan Potassium, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-AGTR1 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
western blot
Anti-AGTR1 Antibody, clone 1I12 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
bovine, canine, human, mouse, rat
Application
affinity binding assay
immunocytochemistry
western blot
immunocytochemistry
western blot
Anti-AGTR1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, human, mouse, rabbit, rat, sheep
Application
western blot
Anti-AT1 Receptor Antibody, Chemicon®, from rabbit,
Species Reactivity
human, mouse, rat
Application
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Anti-AGTR1/AT1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse
Application
ELISA
western blot
western blot
Small Molecule - Inhibitor
Proteins
Product Number
Description
Species
ChemiSCREEN Human Angiotensin II Receptor, Type I Membrane Preparation, Human AT1 GPCR membrane preparation for Radioligand binding Assays & GTPγS binding.,
Species
human
esiRNA
Product Number
Description
Species