ABCG8
ATP-binding cassette, sub-family G (WHITE), member 8
Synonyms:
GBD4, STSL
Species:
Human ABCG8 (64241), Mouse Abcg8 (67470), Rat Abcg8 (155192), domestic guinea pig Abcg8 (100725586), naked mole-rat Abcg8 (101723060), sheep ABCG8 (101113666), Domestic Rabbit ABCG8 (100350554), Zebrafish abcg8 (100136850), chicken ABCG8 (421402), cow ABCG8 (508829) ...More
UniProtKB ID:
Gene ID:
- Human(64241) Summary: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions to exclude non-cholesterol sterol entry at the intestinal level, promote excretion of cholesterol and sterols into bile, and to facilitate transport of sterols back into the intestinal lumen. It is expressed in a tissue-specific manner in the liver, intestine, and gallbladder. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG5. Mutations in this gene may contribute to sterol accumulation and atherosclerosis, and have been observed in patients with sitosterolemia. [provided by RefSeq, Jul 2008]
- Mouse(67470) ATP-binding cassette, sub-family G (WHITE), member 8
- Rat(155192) ATP-binding cassette, subfamily G (WHITE), member 8
- domestic guinea pig(100725586) ATP-binding cassette, sub-family G (WHITE), member 8
- naked mole-rat(101723060) ATP-binding cassette, sub-family G (WHITE), member 8
- sheep(101113666) ATP-binding cassette, sub-family G (WHITE), member 8
- Domestic Rabbit(100350554) ATP-binding cassette, sub-family G (WHITE), member 8
- Zebrafish(100136850) ATP-binding cassette, sub-family G (WHITE), member 8
- chicken(421402) ATP-binding cassette, sub-family G (WHITE), member 8
- cow(508829) ATP-binding cassette, sub-family G (WHITE), member 8
- Horse(100069071) ATP-binding cassette, sub-family G (WHITE), member 8
- domestic cat(101099288) ATP-binding cassette, sub-family G (WHITE), member 8
- dog(474571) ATP-binding cassette, sub-family G (WHITE), member 8
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-ABCG8 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-ABCG8 Antibody, clone 1B10A5, clone 1B10A5, from mouse,
Species Reactivity
human, mouse, rat
Application
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot
immunohistochemistry
immunoprecipitation (IP)
western blot
esiRNA
Product Number
Description
Species