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  • FeCl3 catalyzed Prins-type cyclization for the synthesis of highly substituted indenes: application to the total synthesis of (±)-jungianol and epi-jungianol.

FeCl3 catalyzed Prins-type cyclization for the synthesis of highly substituted indenes: application to the total synthesis of (±)-jungianol and epi-jungianol.

Organic letters (2013-01-16)
Dattatraya H Dethe, Ganesh Murhade
ZUSAMMENFASSUNG

A novel approach was developed for the synthesis of highly substituted indene derivatives, using an FeCl(3) catalyzed Prins-type cyclization reaction which was further applied in the total synthesis of jungianol and epi-jungianol.

MATERIALIEN
Produktnummer
Marke
Produktbeschreibung

Sigma-Aldrich
Eisen(III)-chlorid Hexahydrat, ACS reagent, 97%
Sigma-Aldrich
Eisen(III)-chlorid Hexahydrat, reagent grade, ≥98%, chunks
Sigma-Aldrich
Eisen(III)-chlorid Hexahydrat, puriss. p.a., ACS reagent, crystallized, 98.0-102% (RT)
Sigma-Aldrich
Eisen(III)-chlorid, sublimed grade, ≥99.9% trace metals basis
Sigma-Aldrich
Eisen(III)-chlorid, anhydrous, powder, ≥99.99% trace metals basis
Sigma-Aldrich
Eisen(III)-chlorid -Lösung, purum, 45% FeCl3 basis
Sigma-Aldrich
Eisen(III)-chlorid, 0.2 M in 2-methyltetrahydrofuran
Millipore
TDA-Reagenz, suitable for microbiology