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Merck

1592409

USP

Quercetin

United States Pharmacopeia (USP) Reference Standard

Synonym(e):

Quercetin Dihydrat, 2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-1-benzopyran-4-on Dihydrat, 3,3′,4′,5,7-Pentahydroxy-flavon Dihydrat

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About This Item

Empirische Formel (Hill-System):
C15H10O7 · 2H2O
CAS-Nummer:
Molekulargewicht:
338.27
Farbindexnummer:
75670
Beilstein:
317313
UNSPSC-Code:
41116107
NACRES:
NA.24

Qualität

pharmaceutical primary standard

API-Familie

quercetin

Hersteller/Markenname

USP

mp (Schmelzpunkt)

>300 °C (lit.)

Anwendung(en)

pharmaceutical (small molecule)

Format

neat

Lagertemp.

−20°C

SMILES String

OC(C(O)=C1)=CC=C1C2=C(O)C(C3=C(O)C=C(O)C=C3O2)=O

InChI

1S/C15H10O7.2H2O/c16-7-4-10(19)12-11(5-7)22-15(14(21)13(12)20)6-1-2-8(17)9(18)3-6;;/h1-5,16-19,21H;2*1H2

InChIKey

GMGIWEZSKCNYSW-UHFFFAOYSA-N

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Allgemeine Beschreibung

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Anwendung

Quercetin USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.
Also, for use with USP monographs such as:
  • Cranberry Fruit Juice Dry Extract
  • Japanese Sophora Flower
  • Japanese Sophora Flower Powder
  • Japanese Sophora Flower Bud
  • Japanese Sophora Flower Dry Extract
  • Cranberry Fruit Juice Dry Extract Capsules
  • Rutin

Biochem./physiol. Wirkung

Quercetin-Dihydrat ist ein Flavonoid mit Antitumor-Aktivität. Quercetin ist ein Hemmer der mitochondrialen ATPase und Phosphodiesterase. Es hemmt die PI3-Kinase-Aktivität und hemmt leicht die PIP-Kinase-Aktivität. Quercetin hat antiproliferative Wirkung auf Krebszelllinien, reduziert das Wachstum von Krebszellen über Typ-II-Östrogen-Rezeptoren und hält menschliche leukämischeT-Zellen in der späten G1-Phase des Zellzyklus.

Hinweis zur Analyse

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Sonstige Hinweise

Sales restrictions may apply.

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Piktogramme

Skull and crossbones

Signalwort

Danger

H-Sätze

Gefahreneinstufungen

Acute Tox. 3 Oral

Lagerklassenschlüssel

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 1


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