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Merck

1075757

USP

Bisoprololfumarat

United States Pharmacopeia (USP) Reference Standard

Synonym(e):

Bisoprolol -hemifumarat (Salz), 1-[4-[[2-(1-Methylethoxy)-ethoxy]-methyl]-phenoxy]-3-[(1-methylethyl)-amino]-2-propanol -hemifumarat (Salz)

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About This Item

Empirische Formel (Hill-System):
C18H31NO4 · .5C4H4O4
CAS-Nummer:
Molekulargewicht:
383.48
MDL-Nummer:
UNSPSC-Code:
41116107
PubChem Substanz-ID:
NACRES:
NA.24

Qualität

pharmaceutical primary standard

API-Familie

bisoprolol

Hersteller/Markenname

USP

Anwendung(en)

pharmaceutical (small molecule)

Format

neat

SMILES String

OC(=O)\C=C\C(O)=O.CC(C)NCC(O)COc1ccc(COCCOC(C)C)cc1.CC(C)NCC(O)COc2ccc(COCCOC(C)C)cc2

InChI

1S/2C18H31NO4.C4H4O4/c2*1-14(2)19-11-17(20)13-23-18-7-5-16(6-8-18)12-21-9-10-22-15(3)4;5-3(6)1-2-4(7)8/h2*5-8,14-15,17,19-20H,9-13H2,1-4H3;1-2H,(H,5,6)(H,7,8)/b;;2-1+

InChIKey

VMDFASMUILANOL-WXXKFALUSA-N

Angaben zum Gen

human ... ADRB1(153)

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Allgemeine Beschreibung

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Anwendung


  • Chromatographic Techniques for Assessment of Bisoprolol Fumarate and Perindopril Arginine in Solid Formulations under Various Stress Conditions and Application to Six Sigma, Content Uniformity, and Comparative Dissolution Approaches - Presents advanced chromatographic methods to assess Bisoprolol fumarate in pharmaceutical formulations, crucial for ensuring high standards in drug quality and stability (Mahmoud OA et al., 2023).

Biochem./physiol. Wirkung

Kardioselektiver β1-Adrenozeptor-Antagonist.

Hinweis zur Analyse

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Sonstige Hinweise

Sales restrictions may apply.

Piktogramme

Exclamation markHealth hazard

Signalwort

Warning

Gefahreneinstufungen

Acute Tox. 4 Oral - Repr. 2 - STOT RE 2

Zielorgane

Heart

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Literature data relevant to the decision to allow a waiver of in vivo bioequivalence (BE) testing for the approval of immediate-release (IR) solid oral dosage forms containing bisoprolol as the sole active pharmaceutical ingredient (API) are reviewed. Bisoprolol is classified
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