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SML0647

Sigma-Aldrich

Phenazepam

≥97% (HPLC)

Synonym(e):

7-Bromo-5-(2-chlorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one, 7-Bromo-5-(2-chlorophenyl)-1,3-dihydrobenzo[e]-1,4-diazepin-2-one, BD 98, Fenazepam

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About This Item

Empirische Formel (Hill-System):
C15H10BrClN2O
CAS-Nummer:
51753-57-2
Molekulargewicht:
349.61
UNSPSC-Code:
12352200
NACRES:
NA.77

Qualitätsniveau

100

Assay

≥97% (HPLC)

Form

powder

Farbe

white to beige

Löslichkeit

DMSO: 20 mg/mL, clear

Lagertemp.

−20°C

InChI

1S/C15H10BrClN2O/c16-9-5-6-13-11(7-9)15(18-8-14(20)19-13)10-3-1-2-4-12(10)17/h1-7H,8H2,(H,19,20)

InChIKey

CGMJQQJSWIRRRL-UHFFFAOYSA-N

Biochem./physiol. Wirkung

Phenazepam is the benzodiazepine that exhibit anticonvulsive, anxiolytic, sedative and hypnotic effects in humans and experimental animals. Phenazepam is an agonist of the γ-Aminobutyric acid A (GABAA)-benzodiazepine receptor chloride channel complex.

Leistungsmerkmale und Vorteile

This compound is featured on the GABAA Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Piktogramme

Exclamation markHealth hazard
GHS07,GHS08

Signalwort

Danger

Gefahreneinstufungen

Eye Irrit. 2 - Lact. - Muta. 1B - Repr. 1B

Lagerklassenschlüssel

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

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[Evaluation of the effect of phenazepam and seduxen on the functional state of the cardiovascular system in the acute phase of an infarct].
G Lukhanana
Vrachebnoe delo, (10)(10), 15-18 (1983-10-01)
N Ia Golovenko et al.
Farmakologiia i toksikologiia, 43(2), 144-148 (1980-03-01)
The distribution pattern of 14C-phenazepam and some of its metabolites in the liver, brain and blood plasma at a prolonged (45 days) administration to rats does not differ from that after a single administration. The liver and brain demonstrated an
Peter D Maskell et al.
Journal of forensic and legal medicine, 19(3), 122-125 (2012-03-07)
In the past few years there has been concern in Western Europe and in the US about the rise in abuse of phenazepam, a benzodiazepine that was originally developed in the USSR in the mid- to late 1970s.(1-4) Although phenazepam
Jon B Stephenson et al.
Journal of analytical toxicology, 37(1), 25-29 (2012-10-18)
Phenazepam use in the state of Georgia has increasingly become a trend for a drug market looking at new and different recreational drugs. This paper examines the psychomotor effects of phenazepam on individuals and their ability to operate a motor
John Martin Corkery et al.
Human psychopharmacology, 27(3), 254-261 (2012-03-13)
Phenazepam (fenazepam; 7-bromo-5-(2-chlorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one; PNZ, 'Bonsai') is a benzodiazepine developed in the former Soviet Union during the 1970s to treat neurological disorders, epilepsy, and alcohol withdrawal syndrome. Its recreational use appears to have increased over recent years. Because of the lack

Artikel

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