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Key Documents

SAB4300006

Sigma-Aldrich

Anti-phospho-GSK3A (pSer21) antibody produced in rabbit

affinity isolated antibody

Synonym(e):

Anti-DKFZp686D0638 antibody produced in rabbit, Anti-glycogen synthase kinase 3 alpha antibody produced in rabbit

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About This Item

UNSPSC-Code:
12352203
NACRES:
NA.41

Biologische Quelle

rabbit

Konjugat

unconjugated

Antikörperform

affinity isolated antibody

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Form

buffered aqueous solution

Mol-Gew.

~51 kDa

Speziesreaktivität

mouse, human, rat

Konzentration

1 mg/mL

Methode(n)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100
indirect immunofluorescence: 1:100-1:200
western blot: 1:500-1:1000

Isotyp

IgG

Immunogene Sequenz

(T-S-SP-F-A)

NCBI-Hinterlegungsnummer

NP_063937.2

UniProt-Hinterlegungsnummer

P49840

Versandbedingung

wet ice

Lagertemp.

−20°C

Posttranslationale Modifikation Target

phosphorylation (pSer21)

Angaben zum Gen

human ... GSK3A(2931)

Immunogen

Peptide sequence around phosphorylation site of serine 21 (T-S-S(p)-F-A), according to the protein GSK3A.

Leistungsmerkmale und Vorteile

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Zielbeschreibung

Implicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB and the transcription factor JUN.

Physikalische Form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

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Scientific reports, 7(1), 3815-3815 (2017-06-21)
The molecular mechanisms of thymosin beta-4 (TB4) involved in regulating hepatic stellate cell (HSC) functions remain unclear. Therefore, we hypothesize that TB4 influences HSC activation through hedgehog (Hh) pathway. HSC functions declined in a TB4 siRNA-treated LX-2. TB4 suppression down-regulated
Long He et al.
Proceedings of the National Academy of Sciences of the United States of America, 116(39), 19523-19529 (2019-09-08)
The mTORC1 pathway regulates cell growth and proliferation by properly coupling critical processes such as gene expression, protein translation, and metabolism to the availability of growth factors and hormones, nutrients, cellular energetics, oxygen status, and cell stress. Although multiple cytoplasmic
Donghyun Kim et al.
Medicine and science in sports and exercise, 49(4), 676-686 (2016-11-23)
Little is known regarding the therapeutic role of exercise against the risk of a high-fat diet (HFD) for Alzheimer's disease (AD) and AD-like cognitive deficits. This study aimed to investigate the therapeutic effect of treadmill running against HFD-induced progression in

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