M8693

Melanotan II acetate salt

≥95% (HPLC)

• Synonym(e): Ac-[Nle⁴Asp⁵D-Phe⁷Lys¹⁰]α-MSH-(4-10)-NH₂
• Empirische Formel (Hill-System): C₅₀H₆₉N₁₅O₉ · xC₂H₄O₂
• CAS-Nummer: 121062-08-6
• Molekulargewicht: 1024.18 (free base basis)
• MDL-Nummer: MFCD06795842
• UNSPSC-Code: 51111800
• NACRES: NA.32

Eigenschaften

• Assay: ≥95% (HPLC)
• Form: lyophilized solid
• Farbe: white
• Löslichkeit: H₂O: soluble 5 mg/mL
• Versandbedingung: dry ice
• Lagertemp.: −20°C
• InChI: 1S/C50H69N15O9/c1-3-4-16-36(59-29(2)66)44(69)65-41-25-42(67)55-20-11-10-18-35(43(51)68)60-47(72)39(23-31-26-57-34-17-9-8-15-33(31)34)63-45(70)37(19-12-21-56-50(52)53)61-46(71)38(22-30-13-6-5-7-14-30)62-48(73)40(64-49(41)74)24-32-27-54-28-58-32/h5-9,13-15,17,26-28,35-41,57H,3-4,10-12,16,18-25H2,1-2H3,(H2,51,68)(H,54,58)(H,55,67)(H,59,66)(H,60,72)(H,61,71)(H,62,73)(H,63,70)(H,64,74)(H,65,69)(H4,52,53,56)/t35-,36-,37-,38+,39-,40-,41-/m0/s1
• InChIKey: JDKLPDJLXHXHNV-MFVUMRCOSA-N
• Angaben zum Gen: human ... MC3R(4159) , MC4R(4160) ; mouse ... MC3R(17201) , MC4R(17202) ; rat ... MC3R(29310) , MC4R(25635)

Beschreibung

Amino Acid Sequence

Ac-Nle-Asp-His-Phe-Arg-Trp-Lys-NH2

Allgemeine Beschreibung

Melanotan II induces melanogenesis and thus increases skin pigmentation. It is an analog of α-melanocyte stimulating hormone.

Anwendung

Melanotan II acetate salt has been used to study its inhibitory effects on feeding and energy expenditure in rats.

Biochem./physiol. Wirkung

Melanotan II is a MC3-R/MC4-R melanocortin agonist.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)