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T2200000

Trimethoprim

European Pharmacopoeia (EP) Reference Standard

Synonym(e):

2,4-Diamino-5-(3,4,5-trimethoxybenzyl)pyrimidin, NSC 106568

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About This Item

Empirische Formel (Hill-System):
C14H18N4O3
CAS-Nummer:
738-70-5
Molekulargewicht:
290.32
Beilstein:
625127
MDL-Nummer:
MFCD00036761
UNSPSC-Code:
41116107
PubChem Substanz-ID:
329826703
NACRES:
NA.24

Qualität

pharmaceutical primary standard

API-Familie

trimethoprim

Hersteller/Markenname

EDQM

Anwendung(en)

pharmaceutical (small molecule)

Format

neat

Lagertemp.

2-8°C

SMILES String

COc1cc(Cc2cnc(N)nc2N)cc(OC)c1OC

InChI

1S/C14H18N4O3/c1-19-10-5-8(6-11(20-2)12(10)21-3)4-9-7-17-14(16)18-13(9)15/h5-7H,4H2,1-3H3,(H4,15,16,17,18)

InChIKey

IEDVJHCEMCRBQM-UHFFFAOYSA-N

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Allgemeine Beschreibung

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Anwendung

Antibakterieller Wirkstoff, Dihydrofolatreduktase-Inhibitor mit Selektivität für prokaryotische Enzyme.

Verpackung

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Sonstige Hinweise

Sales restrictions may apply.

Piktogramme

Health hazardExclamation mark
GHS08,GHS07

Signalwort

Warning

H-Sätze

H302,H361d

Gefahreneinstufungen

Acute Tox. 4 Oral - Repr. 2

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

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Analysenzertifikate (COA)

Lot/Batch Number

Sorry, we don't have COAs for this product available online at this time.

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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

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O Sköld
Veterinary research, 32(3-4), 261-273 (2001-07-04)
Sulfonamides and trimethoprim have been used for many decades as efficient and inexpensive antibacterial agents for animals and man. Resistance to both has, however, spread extensively and rapidly. This is mainly due to the horizontal spread of resistance genes, expressing
Christine Manyando et al.
PloS one, 9(5), e96017-e96017 (2014-05-17)
Antibiotic therapy during pregnancy may be beneficial and impacts positively on the reduction of adverse pregnancy outcomes. No studies have been done so far on the effects of daily Co-trimoxazole (CTX) prophylaxis on birth outcomes. A phase 3b randomized trial
Dolores Camacho-Muñoz et al.
Chemosphere, 111, 70-79 (2014-07-07)
The distribution of pharmaceutically active compounds in the environment has been reported in several works in which wastewater treatment plants have been identified as the main source of these compounds to the environment. The concentrations of these compounds in influent
Luis H Braga et al.
The Journal of urology, 191(5 Suppl), 1501-1507 (2014-04-01)
We determined the feasibility of a clinical trial of continuous antibiotic prophylaxis to prevent urinary tract infections in children with prenatal hydronephrosis. We piloted a blinded, randomized, placebo controlled study of the urinary tract infection rate in infants with grades
Adverse reactions to sulphonamide and sulphonamide-trimethoprim antimicrobials: clinical syndromes and pathogenesis.
A E Cribb et al.
Adverse drug reactions and toxicological reviews, 15(1), 9-50 (1996-03-01)
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