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Merck

32677

Supelco

Difenacoum

PESTANAL®, analytical standard

Synonym(e):

3-(3-Biphenyl-4-yl-1,2,3,4-tetrahydro-1-naphthyl)-4-hydroxy-cumarin, 3-(3-Biphenyl-4-yl-1,2,3,4-tetrahydro-naphthalin-1-yl)-4-hydroxy-chromen-2-on

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About This Item

Empirische Formel (Hill-System):
C31H24O3
CAS-Nummer:
Molekulargewicht:
444.52
Beilstein:
8360065
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
41116107
PubChem Substanz-ID:
NACRES:
NA.24

Qualität

analytical standard

Qualitätsniveau

Produktlinie

PESTANAL®

Haltbarkeit

limited shelf life, expiry date on the label

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

Anwendung(en)

agriculture
environmental

Format

neat

SMILES String

OC1=C(C2CC(Cc3ccccc23)c4ccc(cc4)-c5ccccc5)C(=O)Oc6ccccc16

InChI

1S/C31H24O3/c32-30-26-12-6-7-13-28(26)34-31(33)29(30)27-19-24(18-23-10-4-5-11-25(23)27)22-16-14-21(15-17-22)20-8-2-1-3-9-20/h1-17,24,27,32H,18-19H2

InChIKey

FVQITOLOYMWVFU-UHFFFAOYSA-N

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Allgemeine Beschreibung

Difenacoum is a coumarin anticoagulant, which is developed as a rodenticide, in order to control warfarin‐resistant rodents.

Anwendung

Difenacoum may be used as a reference standard in the determination of difenacoum in tissue samples using high performance liquid chromatography (HPLC).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Rechtliche Hinweise

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Signalwort

Danger

Gefahreneinstufungen

Acute Tox. 1 Dermal - Acute Tox. 1 Inhalation - Acute Tox. 1 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 1B - STOT RE 1

Zielorgane

Blood

Lagerklassenschlüssel

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges


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Analysenzertifikate (COA)

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Die Dokumentenbibliothek aufrufen

Determination of coumarin anticoagulant rodenticide residues in animal tissue by high-performance liquid chromatography: I. Fluorescence detection using post-column techniques.
Hunter K, et al.
Journal of Chromatography A, 270, 267-276 (1983)
Stefan Endepols et al.
Pest management science, 69(3), 409-413 (2012-04-25)
Field studies guided by genetic monitoring of Vkorc1 need to be done to implicate mutations conclusively with rodent control problems due to the presence of animals resistant to anticoagulant rodenticides. Rodent control success in relation to Vkorc1 genotypes in house
J E Gill et al.
Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 104(1), 29-36 (1993-01-01)
1. A new test for identifying levels of difenacoum resistance in the Norway rat is described, based upon the differential physiological response to difenacoum administration. 2. This test is based on changes in blood clotting activity over 4 days, following
Helen Atterby et al.
Environmental toxicology and chemistry, 24(2), 318-323 (2005-02-22)
The present study investigated the whole-carcass residue carried by resistant and susceptible laboratory rat strains following 5, 10, or 20 d of feeding on a diet of 25 mg difenacoum/kg bait. The mean whole-carcass residue of difenacoum was determined by
Field trials of second-generation anticoagulants against difenacoum-resistant Norway rat population.
Greaves HJ, et al.
Epidem. Inf., 89(2), 295-301 (1982)

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