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Merck

MAB5228

Sigma-Aldrich

Anti-Amyloid Precursor Protein Antibody, Secretory, clone OM84

clone OM84, Chemicon®, from mouse

Synonym(e):

APP

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About This Item

UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Biologische Quelle

mouse

Qualitätsniveau

Antikörperform

purified immunoglobulin

Antikörper-Produkttyp

primary antibodies

Klon

OM84, monoclonal

Speziesreaktivität

human

Hersteller/Markenname

Chemicon®

Methode(n)

ELISA: suitable
western blot: suitable

Isotyp

IgG2aκ

NCBI-Hinterlegungsnummer

UniProt-Hinterlegungsnummer

Versandbedingung

dry ice

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... APP(351)

Spezifität

Reacts with secretory amyloid precursor protein (sAPP), but not with Amyloid-Beta protein 1-40.

Immunogen

Amyloid Precursor Protein (APP) secreted by the EJ-1 bladder carcinoma cell line.
Epitope: Secretory

Anwendung

Research Category
Neurowissenschaft
Research Sub Category
Neurodegenerative Krankheiten
Anti-Amyloid Precursor Protein Antibody, Secretory, clone OM84 detects level of Amyloid Precursor Protein & has been published & validated for use in ELISA & WB.
Western blot: 10 μg/mL ELISA: 1 μg/mL

Optimal working dilutions must be determined by end user.

Physikalische Form

Protein A purified
Format: Purified
Protein A Purified mouse immunoglobulin in 10 mM sodium phosphate buffer (pH 7.4), 0.15 M NaCl, and 0.1% sodium azide as a preservative..

Lagerung und Haltbarkeit

Maintain frozen at -70°C or below in undiluted aliquots for up to 12 months, avoid repeated freeze/thaw cycles.

Hinweis zur Analyse

Control
Brain

Sonstige Hinweise

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Rechtliche Hinweise

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

12 - Non Combustible Liquids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Dual roles of the transmembrane protein p23/TMP21 in the modulation of amyloid precursor protein metabolism
Vetrivel, Kulandaivelu S, et al.
Mol. Neurodegener., 2, 4-4 (2007)
A novel actin-binding domain on Slo1 calcium-activated potassium channels is necessary for their expression in the plasma membrane.
Zou, S; Jha, S; Kim, EY; Dryer, SE
Molecular Pharmacology null
Christine Römer et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(20), 7777-7794 (2015-05-23)
Stroke-induced immunodepression (SIDS) is an essential cause of poststroke infections. Pharmacological inhibition of SIDS appears promising in preventing life-threatening infections in stroke patients. However, SIDS might represent an adaptive mechanism preventing autoreactive immune responses after stroke. To address this, we
Ellen Sapp et al.
Neurobiology of disease, 141, 104950-104950 (2020-05-23)
Molecular changes at synapses are thought to underly the deficits in motor and cognitive dysfunction seen in Huntington's disease (HD). Previously we showed in synaptosome preparations age dependent changes in levels of selected proteins examined by western blot assay in

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