14-700
NEK11 Protein, active, 10 µg
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About This Item
eCl@ss:
32160405
Rekombinant
expressed in baculovirus infected Sf21 cells
Qualitätsniveau
Beschreibung
protein target NEK11
Aufgereinigt durch
(Ni2+/NTA-agarose)
Methode(n)
activity assay: suitable
UniProt-Hinterlegungsnummer
Angaben zum Gen
human ... NEK11(79858)
Allgemeine Beschreibung
FUNCTION: SwissProt: Q8NG66 # Possible role in S-phase checkpoint mechanism.
COFACTOR: Manganese or magnesium.
SIZE: 645 amino acids; 74162 Da
SUBCELLULAR LOCATION: Nucleus. Nucleus, nucleolus. Note=Nuclear during interphase but moves to the polar microtubules during prometaphase and metaphase. Accumulates in the nucleolus in G1/S- arrested cells.
TISSUE SPECIFICITY: Poorly expressed in cerebellum, trachea, lung, appendix, and uterus.
DEVELOPMENTAL STAGE: Predominantly expressed at S/G2/M phase.
PTM: Phosphorylated.
SIMILARITY: SwissProt: Q8NG66 ## Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. NIMA subfamily. & Contains 1 protein kinase domain.
COFACTOR: Manganese or magnesium.
SIZE: 645 amino acids; 74162 Da
SUBCELLULAR LOCATION: Nucleus. Nucleus, nucleolus. Note=Nuclear during interphase but moves to the polar microtubules during prometaphase and metaphase. Accumulates in the nucleolus in G1/S- arrested cells.
TISSUE SPECIFICITY: Poorly expressed in cerebellum, trachea, lung, appendix, and uterus.
DEVELOPMENTAL STAGE: Predominantly expressed at S/G2/M phase.
PTM: Phosphorylated.
SIMILARITY: SwissProt: Q8NG66 ## Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. NIMA subfamily. & Contains 1 protein kinase domain.
Qualität
routinely evaluated by phosphorylation of MBP (Catalog # 13-104)
Physikalische Eigenschaften
59.3kDa
Lagerung und Haltbarkeit
6 months at -70°C from date of shipment
Hinweis zur Analyse
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Haftungsausschluss
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Signalwort
Warning
H-Sätze
Gefahreneinstufungen
Skin Sens. 1
Lagerklassenschlüssel
12 - Non Combustible Liquids
WGK
WGK 1
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
Analysenzertifikate (COA)
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