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Sigma-Aldrich

Baicalin

95%

Synonym(e):

Baicalein-7-O-β-D-glucuronid

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About This Item

Empirische Formel (Hill-System):
C21H18O11
CAS-Nummer:
21967-41-9
Molekulargewicht:
446.36
MDL-Nummer:
MFCD00134418
UNSPSC-Code:
12352201
PubChem Substanz-ID:
24880654
NACRES:
NA.22

Assay

95%

Form

solid

Optische Aktivität

[α]20/D −85°, c = 1 in DMSO

mp (Schmelzpunkt)

202-205 °C (dec.) (lit.)

SMILES String

O[C@@H]1[C@@H](O)[C@@H](O[C@@H]([C@H]1O)C(O)=O)Oc2cc3OC(=CC(=O)c3c(O)c2O)c4ccccc4

InChI

1S/C21H18O11/c22-9-6-10(8-4-2-1-3-5-8)30-11-7-12(14(23)15(24)13(9)11)31-21-18(27)16(25)17(26)19(32-21)20(28)29/h1-7,16-19,21,23-27H,(H,28,29)/t16-,17-,18+,19-,21+/m0/s1

InChIKey

IKIIZLYTISPENI-ZFORQUDYSA-N

Angaben zum Gen

mouse ... Hexa(15211)

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Allgemeine Beschreibung

Baicalin is a key flavonoid found in the roots of Scutellaria baicalensis. It is known to have different biological activities, such as anti-oxidative, anti-inflammatory, antitumor and anti-apoptotic activities.

Anwendung

Baicalin has been used in a study to examine its neuroprotective effect in chronically stressed rats.2

Piktogramme

Exclamation mark
GHS07

Signalwort

Warning

H-Sätze

H302

Gefahreneinstufungen

Acute Tox. 4 Oral

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Gloves

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Paeoniflorin ≥98% (HPLC)

Sigma-Aldrich

P0038

Paeoniflorin

Baicalein A cell-permeable flavone that inhibits the activity of 12-lipoxygenase (IC₅₀= 120 nM) and reverse transcriptase.

Sigma-Aldrich

196322

Baicalein

Scutellarin hydrate ≥98% (HPLC)

Sigma-Aldrich

SML0014

Scutellarin hydrate

Schisandrin ≥98% (HPLC)

Sigma-Aldrich

SML0054

Schisandrin

Gomisin A

Sigma-Aldrich

SML1251

Gomisin A

Leonurine ≥98% (HPLC)

Sigma-Aldrich

SML0670

Leonurine

Baicalin Attenuates Hypoxia-Induced Pulmonary Arterial Hypertension to Improve Hypoxic Cor Pulmonale by Reducing the Activity of the p38 MAPK Signaling Pathway and MMP-9.
Yan S, et al.
Evidence-Based Complementary and Alternative Medicine : ECAM, 2016 (2016)
Baicalin influences the dendritic morphology of newborn neurons in the hippocampus of chronically stressed rats.
Jiang X, et al.
Neural Regeneration Research, 8(6), 496-496 (2013)
Peng-Fei Yue et al.
International journal of pharmaceutics, 443(1-2), 279-287 (2013-01-08)
Baicalin nanosuspensions, stabilized with 10% TPGS (relative to the weight of baicalin), were transformed into nanosuspensions powders by solidification process. Solidification methods for this transformation included freeze-drying, spray drying or vacuum drying. High pressure homogenization was applied for production of
Peng-Wei Zhuang et al.
CNS neuroscience & therapeutics, 19(3), 154-162 (2013-01-11)
Recent studies revealed that baicalin, a flavonoid compound derived from the root of Scutellaria baicalensis Georgi, could promote neuron differentiation of NSPCs after commencing the differentiation process in vitro. However, this may not be the most efficacious strategy to determinate
Qi Wang et al.
Molecular and cellular biochemistry, 463(1-2), 91-100 (2019-10-14)
Baicalin (BAI), a sort of flavonoid monomer, acquires from Scutellaria baicalensis Georgi, which was forcefully reported in diversified ailments due to the pleiotropic properties. But, the functions of BAI in osteoblast differentiation have not been addressed. The intentions of this study
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