SRD5A3
steroid 5 alpha-reductase 3
Synonyme:
CDG1P, CDG1Q, KRIZI, SRD5A2L, SRD5A2L1
Spezies:
Human SRD5A3 (79644), Mouse Srd5a3 (57357), Rat Srd5a3 (305291), Zebrafish srd5a3 (560717), domestic cat SRD5A3 (101090010), dog SRD5A3 (482155), chicken SRD5A3 (422750), cow SRD5A3 (535834), sheep SRD5A3 (101106772), domestic guinea pig Srd5a3 (100727041)
UniProtKB-ID:
Gen-ID:
- Human(79644) Summary: The protein encoded by this gene belongs to the steroid 5-alpha reductase family, and polyprenol reductase subfamily. It is involved in the production of androgen 5-alpha-dihydrotestosterone (DHT) from testosterone, and maintenance of the androgen-androgen receptor activation pathway. This protein is also necessary for the conversion of polyprenol into dolichol, which is required for the synthesis of dolichol-linked monosaccharides and the oligosaccharide precursor used for N-linked glycosylation of proteins. Mutations in this gene are associated with congenital disorder of glycosylation type Iq. [provided by RefSeq, Mar 2011]
- Mouse(57357) steroid 5 alpha-reductase 3
- Rat(305291) steroid 5 alpha-reductase 3
- Zebrafish(560717) steroid 5 alpha-reductase 3
- domestic cat(101090010) steroid 5 alpha-reductase 3
- dog(482155) steroid 5 alpha-reductase 3
- chicken(422750) steroid 5 alpha-reductase 3
- cow(535834) steroid 5 alpha-reductase 3
- sheep(101106772) steroid 5 alpha-reductase 3
- domestic guinea pig(100727041) steroid 5 alpha-reductase 3
- naked mole-rat(101726767) steroid 5 alpha-reductase 3
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Small Molecule - Inhibitor
Produktnummer
Beschreibung
Spezies
Dutasterid für die Systemeignung, European Pharmacopoeia (EP) Reference Standard,
Spezies
human