LFNG
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
Synonyme:
SCDO3
Spezies:
Human LFNG (3955), Mouse Lfng (16848), Rat Lfng (170905), Zebrafish lfng (30158), dog LFNG (489891), chicken LFNG (395790), cow LFNG (516209), domestic guinea pig Lfng (100730084), naked mole-rat Lfng (101699763), sheep LFNG (101112372)
UniProtKB-ID:
Gen-ID:
- Human(3955) Summary: This gene is a member of the fringe gene family which also includes radical and manic fringe genes. They all encode evolutionarily conserved glycosyltransferases that act in the Notch signaling pathway to define boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, fringe proteins have a fucose-specific beta-1,3-N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling. This gene product is predicted to be a single-pass type II Golgi membrane protein but it may also be secreted and proteolytically processed like the related proteins in mouse and Drosophila (PMID: 9187150). Mutations in this gene have been associated with autosomal recessive spondylocostal dysostosis 3. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
- Mouse(16848) LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
- Rat(170905) LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
- Zebrafish(30158) lunatic fringe homolog
- dog(489891) LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
- chicken(395790) LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
- cow(516209) LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
- domestic guinea pig(100730084) LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
- naked mole-rat(101699763) LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
- sheep(101112372) LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
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Antibodies
Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-LFNG antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunohistochemistry
western blot
western blot
Monoclonal Anti-LFNG antibody produced in mouse, clone 1B6, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
ELISA
western blot
western blot
Anti-LFNG antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
western blot
Monoclonal Anti-LFNG antibody produced in mouse, clone 1F9, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human, mouse
Anwendung
ELISA
western blot
western blot
Monoclonal Anti-LFNG antibody produced in mouse, clone 4F8, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
ELISA
immunoprecipitation (IP)
immunoprecipitation (IP)
esiRNA
Produktnummer
Beschreibung
Spezies