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GABRG3

gamma-aminobutyric acid (GABA) A receptor, gamma 3

Synonyme:
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(2567) Summary: This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. The protein encoded by this gene is a gamma subunit, which contains the benzodiazepine binding site. Two transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Aug 2012]
  • Mouse(14407) gamma-aminobutyric acid (GABA) A receptor, subunit gamma 3
  • Rat(79211) gamma-aminobutyric acid (GABA) A receptor, gamma 3
  • domestic guinea pig(100729690) gamma-aminobutyric acid (GABA) A receptor, gamma 3
  • naked mole-rat(101712623) gamma-aminobutyric acid (GABA) A receptor, gamma 3
  • sheep(101108521) gamma-aminobutyric acid (GABA) A receptor, gamma 3
  • Zebrafish(567057) gamma-aminobutyric acid (GABA) A receptor, gamma 3
  • cow(613670) gamma-aminobutyric acid (GABA) A receptor, gamma 3
  • domestic cat(101094182) gamma-aminobutyric acid (GABA) A receptor, gamma 3
  • dog(488685) gamma-aminobutyric acid (GABA) A receptor, gamma 3
  • chicken(770097) gamma-aminobutyric acid (GABA) A receptor, gamma 3

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Small Molecule - Agonist

Produktnummer
Beschreibung
Spezies
2-Brom-2-chlor-1,1,1-trifluorethan, ≥99%,
Spezies
human

Small Molecule - Allosteric Modulator

Produktnummer
Beschreibung
Spezies
Etomidat, >98% (HPLC), powder,
Spezies
human
Etomidat, United States Pharmacopeia (USP) Reference Standard,
Spezies
human
Propofol, United States Pharmacopeia (USP) Reference Standard,
Spezies
human
Flunitrazepam, British Pharmacopoeia (BP) Reference Standard,
Spezies
human
Propofol, European Pharmacopoeia (EP) Reference Standard,
Spezies
human

Small Molecule - Antagonist

Produktnummer
Beschreibung
Spezies
Flumazenil, United States Pharmacopeia (USP) Reference Standard,
Spezies
human
Ganaxolone, ≥98% (HPLC), solid,
Spezies
human, mouse
2,6-Diisopropylphenol, 97%,
Spezies
human
Flumazenil, >99% (HPLC), solid,
Spezies
rat, human
5α-Pregnan-3α-ol-20-one, solid,
Spezies
human, mouse, rat

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-GABRG3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunohistochemistry
Anti-GABRG3 antibody produced in rabbit, IgG fraction of antiserum,
Speziesreaktivität
human
Anwendung
western blot

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human GABRG3,
Spezies
human