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  • EZH2 deletion in early mesenchyme compromises postnatal bone microarchitecture and structural integrity and accelerates remodeling.

EZH2 deletion in early mesenchyme compromises postnatal bone microarchitecture and structural integrity and accelerates remodeling.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology (2016-12-10)
Sarah Hemming, Dimitrios Cakouros, John Codrington, Kate Vandyke, Agneiszka Arthur, Andrew Zannettino, Stan Gronthos
RESUMEN

In this study, we examined the functional importance of EZH2 during skeletal development and homeostasis using the conditional deletion of

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Sodium pyruvate solution, 100 mM, sterile-filtered, BioReagent, suitable for cell culture
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Medio esencial mínimo Eagle, Alpha Modification, with sodium bicarbonate, without L-glutamine, ribonucleosides and deoxyribonucleosides, liquid, sterile-filtered, suitable for cell culture
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Anticuerpo anti-trimetil-histona H3 (Lys27), Upstate®, from rabbit
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Ser-Phe-Leu-Leu-Arg-Asn-Pro-Asn-Asp-Lys-Tyr-Glu-Pro-Phe, ≥97% (HPLC)