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Merck

Palladium-Catalyzed Directed C(sp

European journal of organic chemistry (2016-02-16)
Dominic P Affron, James A Bull
RESUMEN

Saturated heterocycles, such as THFs, pyrrolidines, piperidines and THPs, are essential components of many biologically active compounds. Examples of C-H functionalization on these important ring systems remain scarce, especially at unactivated positions. Here we report the development of conditions for the palladium-catalyzed stereoselective C(sp