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Merck

Rhodopsin phosphorylation: from terminating single photon responses to photoreceptor dark adaptation.

Trends in neurosciences (2002-02-20)
Vadim Y Arshavsky
RESUMEN

Rhodopsin phosphorylation has provided one of the first examples of the ubiquitous regulatory pattern of specific kinases downregulating the activity of G-protein-coupled receptors. However, only recently have studies in living animals allowed us to consider the role of rhodopsin phosphorylation in a broader spectrum of visual functions, ranging from the ability of rods to generate reproducible electrical responses to their ability to adapt to darkness after substantial light exposures.