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The 50th anniversary of the discovery of 6-aminopenicillanic acid (6-APA).

International journal of antimicrobial agents (2006-12-02)
G N Rolinson, A M Geddes
RESUMEN

This year (2007) marks the 50th anniversary of [corrected] discovery of 6-aminopenicillanic acid (6-APA), the precursor of all semi-synthetic penicillins [corrected] This review, by a scientist who played a major part in the discovery and a physician who participated in the early clinical trials of these antibiotics, tells the story of the discovery and of the early development of the beta-lactam antibiotics that revolutionised the treatment of infections.

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(+)-6-Aminopenicillanic acid, 96%
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Flucloxacillin impurity C, European Pharmacopoeia (EP) Reference Standard
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