- [Antagonism of daurisoline on arrhythmogenic delayed afterdepolarization].
[Antagonism of daurisoline on arrhythmogenic delayed afterdepolarization].
Yao xue xue bao = Acta pharmaceutica Sinica (1994-01-01)
Z X Wang, J Q Zhu, F D Zeng, C J Hu
PMID7900534
RESUMEN
Standard microelectrode technique was used to study the effect of daurisoline (DS) on delayed afterdepolarization (DAD) and triggered activity (TA) in guinea pig ventricular trabeculae. DS (50 mumol.L-1) abolished TA induced by ouabain or caffeine, inhibited isoprenaline-induced TA, decreased incidence of TA induced by K(+)-free and high-Ca2+ medium or phenylephrine from 100.75% to 9.1% and 22.2% respectively, and significantly suppressed DAD caused by the above induces. It is concluded that DS exert antagonistic action to DAD and TA in guinea pig trabeculae.
MATERIALES
Referencia del producto
Marca
Descripción del producto
Número de referencia del producto (SKU)
Tamaño de envase
Disponibilidad
Precio
Cantidad