Saltar al contenido
Merck

The functionalisation of saturated hydrocarbons--XXX. Model studies on the mechanism of some oxygenases.

Bioorganic & medicinal chemistry (1994-04-01)
D H Barton, C O Bardin, D Doller
RESUMEN

In harmony with our studies on the activation of hydrocarbons by Gif chemistry, we have, in the first part of this paper, studied the mechanism of the lipoxygenase enzymes using soybean lipoxygenase as a model. We have shown with trimethyl phosphite that no free radical is released by the enzyme. In a second part, we have studied the mechanism of the alpha-ketoglutarate dependent enzymes and shown evidence for a mechanism involving the reduction of an intermediate hydroperoxide by the alpha-ketoglutaric acid.

MATERIALES
Referencia del producto
Marca
Descripción del producto

Sigma-Aldrich
Trimethyl phosphite, ≥99%
Número de referencia del producto (SKU)
Tamaño de envase
Disponibilidad
Precio
Cantidad
Sigma-Aldrich
Trimethyl phosphite, ≥97%
Número de referencia del producto (SKU)
Tamaño de envase
Disponibilidad
Precio
Cantidad