Metabolism of 1H-benzotriazolecarboxylic acids in vitro and in vivo.

The 1H-benzotriazolecarboxylic acids 1 and 2 were stable towards oxidative metabolism as well in vitro as in vivo. In the in vivo studies 2.25% of the ester glucuronide of 1H-benzotriazole-5-carboxylic acid was found in urine.