SML1432

PHCCC

≥97% (HPLC)

• Sinónimos: 7,7a-Dihydro-7-(hydroxyimino)-N-phenyl-benzo[b]cyclopropa[e]pyran-1a(1H)-carboxamide, N-Phenyl-7-(hydroxyimino)cyclopropa[b]chromen-1a-carboxamide
• Fórmula empírica (notación de Hill): C₁₇H₁₄N₂O₃
• Número de CAS: 179068-02-1
• Peso molecular: 294.30
• UNSPSC Code: 12352202
• PubChem Substance ID: 329825873
• NACRES: NA.77

Propiedades

• Quality Level: 100
• assay: ≥97% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 10 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: O=C(NC1=CC=CC=C1)C2(C/3C2)OC4=C(C=CC=C4)C3=N/O
• InChI: 1S/C17H14N2O3/c20-16(18-11-6-2-1-3-7-11)17-10-13(17)15(19-21)12-8-4-5-9-14(12)22-17/h1-9,13,21H,10H2,(H,18,20)/b19-15+
• InChI key: FPXPIEZPAXSELW-XDJHFCHBSA-N

Descripción

Biochem/physiol Actions

PHCCC is a positive allosteric modulator (PAM) at the mGluR4 subtype that exhibits anxiolytic and anti-Parkinsonian effects in animal models. PHCCC is a potent group I metabotropic glutamate receptor antagonist.

Información de seguridad

• pictograms: GHS07
• signalword: Warning
• hcodes: H302
• pcodes: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable