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Merck
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G0674

SAFC

GlycylGlycine

Fabricación farmacéutica

Sinónimos:

Gly-Gly, Diglycine, Glycyl-glycine

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About This Item

Fórmula lineal:
NH2CH2CONHCH2COOH
Número de CAS:
556-50-3
Peso molecular:
132.12
Beilstein/REAXYS Number:
1765223
EC Number:
209-127-8
MDL number:
MFCD00008130
UNSPSC Code:
12352200
NACRES:
NA.21

biological source

synthetic

Quality Level

500

form

powder

impurities

heavy metals, tested

useful pH range

7.5-8.9

pKa (25 °C)

8.2

suitability

suitable for manufacturing use

SMILES string

NCC(=O)NCC(O)=O

InChI

1S/C4H8N2O3/c5-1-3(7)6-2-4(8)9/h1-2,5H2,(H,6,7)(H,8,9)

InChI key

YMAWOPBAYDPSLA-UHFFFAOYSA-N

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General description

Our SAFC® portfolio of high-quality products for biopharmaceutical processing withstands strict quality control procedures and is produced according to MQ-500 requirements as defined by the M-Clarity program.

M-Clarity Program

Our comprehensive portfolio of upstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Trust us to deliver supply chain transparency and reliable sourcing around the globe, streamlining your product qualification with best-in-class regulatory support and service.

Application

Glycylglycine is the dipeptide of glycine and one of the simplest peptides. It also works as a buffering agent.

Legal Information

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

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G C Cook
Gut, 17(4), 252-257 (1976-04-01)
Using a double-lumen tube jejunal perfusion system in vivo, the mutual effects of carnosine (beta-alanyl-L-histidine) and glycylglycine on their respective absorption rates have been studied in six Zambian African adults. Data on the effect of the constituent amino-acids of carnosine
Cumali Efe et al.
European journal of gastroenterology & hepatology, 27(6), 649-654 (2015-04-11)
There are no validated noninvasive markers of liver fibrosis in autoimmune hepatitis (AIH). An activated renin-angiotensin system (RAS) and its key element angiotensin-converting enzyme (ACE) have been implicated in the pathogenesis of hepatic fibrogenesis. We aimed to study the assumed
Armando Tripodi et al.
European journal of internal medicine, 25(5), 449-451 (2014-05-03)
Statins are cholesterol-lowering agents with antithrombotic effect possibly unrelated to their lipid-lowering properties. Traditional global coagulation tests failed, however, to reveal clinically relevant change after treatment. We therefore sought to investigate whether statins were able to modify thrombin generation in
Francis Impens et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(34), 12432-12437 (2014-08-13)
SUMOylation is an essential ubiquitin-like modification involved in important biological processes in eukaryotic cells. Identification of small ubiquitin-related modifier (SUMO)-conjugated residues in proteins is critical for understanding the role of SUMOylation but remains experimentally challenging. We have set up a
Nicole C Narrandes et al.
BMC microbiology, 15, 22-22 (2015-02-06)
Molybdopterin cofactor (MoCo) biosynthesis in Mycobacterium tuberculosis is associated with a multiplicity of genes encoding several enzymes in the pathway, including the molybdopterin (MPT) synthase, a hetero tetramer comprising two MoaD and two MoaE subunits. In addition to moaD1, moaD2
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