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Key Documents

B950-05

Sigma-Aldrich

Bovine Renal Artery Smooth Muscle Cells: BRASMC (Cryovial)

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About This Item

UNSPSC Code:
41106514
NACRES:
NA.81

biological source

bovine renal artery (normal, tunica intima and media)

Quality Level

100

packaging

pkg of 500,000 cells

manufacturer/tradename

Cell Applications, Inc

growth mode

Adherent

karyotype

2n = 60

morphology

smooth muscle

technique(s)

cell culture | mammalian: suitable

relevant disease(s)

renal disease; cardiovascular diseases

shipped in

dry ice

storage temp.

−196°C

General description

Lot specific orders are not able to be placed through the web. Contact your local sales rep for more details.

Bovine Renal Artery Smooth Muscle Cells (BRASMC) are derived from tunica intima and tunica media of normal bovine renal arteries. They are cryopreserved at second passage and can be cultured and propagated at least 12 population doublings. Studies show cyclosporine-induced renal artery smooth muscle contraction is associated with increases in the phosphorylation of specific contractile regulatory proteins1. The renal artery smooth muscle is uniquely refractory to angiotensin stimulation and may be protective in the role of the kidney in regulating blood pressure through the renin-angiotensin system2.

Beall, A. et al, Biochem Biophys Acta., 1449(1):41-9 (1999)
Whitney, E.G. et al, J. Surg. Res. 61(2):307-10 (1996)

Products are for research use only. They are not intended for human, animal, or diagnostic application.
Animal tissues were USDA inspected.

Cell Line Origin

Artery

Application

blood flow to kidneys

Components

Bovine Smooth Muscle Cell Basal Medium containing 10% FBS & 10% DMSO

Preparation Note

  • 2nd passage, >500,000 cells in Bovine Smooth Muscle Cell Basal Medium containing 10% FBS & 10% DMSO
  • Can be cultured at least 12 doublings

Subculture Routine

Please refer to the BRASMC Culture Protocol.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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