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Merck

870432P

Avanti

C18:1 anandamide

Avanti Research - A Croda Brand 870432P, powder

Sinónimos:

9Z-octadecenoylethanolamide

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About This Item

Fórmula empírica (notación de Hill):
C20H39NO2
Número de CAS:
Peso molecular:
325.53
UNSPSC Code:
12352211
NACRES:
NA.25

form

powder

packaging

pkg of 1 × 5 mg (870432P-5mg)

manufacturer/tradename

Avanti Research - A Croda Brand 870432P

lipid type

bioactive lipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

O=C(CCCCCCC/C=C\CCCCCCCC)NCCO

General description

Anandamide is an endocannabinoid. It acts as a ligand for cannabinoid (CB) receptors CB1 and CB2 in the brain and peripheral tissues. It is synthesized from glycerophospho-N-arachidonoylethanolamine (GP-NArE) precursor by the reaction catalyzed by glycerophosphodiesterase 1.

Biochem/physiol Actions

Anandamide plays a vital role in various processes including inflammation, pain, and appetite.

Packaging

5 mL Clear Glass Sealed Ampule (870432P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


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Mohammad Younus et al.
Langmuir : the ACS journal of surfaces and colloids, 32(35), 8942-8950 (2016-08-16)
Oleoylethanolamide (OEA) is an endogenous lipid with neuroprotective properties and the fortification of its concentration in the brain can be beneficial in the treatment of many neurodegenerative disorders. However, OEA is rapidly eliminated by hydrolysis in vivo, limiting its therapeutic
Mohammed K Hankir et al.
Frontiers in neuroscience, 10, 620-620 (2017-01-31)
Brain μ-opioid receptors (MORs) stimulate high-fat (HF) feeding and have been implicated in the distinct long term outcomes on body weight of bariatric surgery and dieting. Whether alterations in fat appetite specifically following these disparate weight loss interventions relate to
Identification of biosynthetic precursors for the endocannabinoid anandamide in the rat brain
Astarita G, et al.
Journal of Lipid Research, 49(1), 48-57 (2008)
Selective blockade of 2-arachidonoylglycerol hydrolysis produces cannabinoid behavioral effects
Long J, et al.
Nature Chemical Biology, 5(1), 37-37 (2009)
Gabriel M Simon et al.
The Journal of biological chemistry, 283(14), 9341-9349 (2008-01-30)
Anandamide (AEA) is an endogenous ligand of cannabinoid receptors and a well characterized mediator of many physiological processes including inflammation, pain, and appetite. The biosynthetic pathway(s) for anandamide and its N-acyl ethanolamine (NAE) congeners remain enigmatic. Previously, we proposed an

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