TPO
thyroid peroxidase
Sinónimos:
MSA, TDH2A, TPX
Especie:
Human TPO (7173), Mouse Tpo (22018), Rat Tpo (54314), cow TPO (525013), naked mole-rat Tpo (101704548), domestic guinea pig Tpo (100723704), chicken TPO (776120), domestic cat TPO (101098706), dog TPO (403521)
ID UniProtKB:
ID del gen:
- Human(7173) Summary: This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, May 2011]
- Mouse(22018) thyroid peroxidase
- Rat(54314) thyroid peroxidase
- cow(525013) thyroid peroxidase
- naked mole-rat(101704548) thyroid peroxidase
- domestic guinea pig(100723704) thyroid peroxidase
- chicken(776120) thyroid peroxidase
- domestic cat(101098706) thyroid peroxidase
- dog(403521) thyroid peroxidase
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Antibodies
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Descripción
Reactividad de especies
Aplicación
Anti-Thyroid Peroxidase Antibody, clone 3C4A4, Rabbit Monoclonal, ,
Reactividad de especies
human, rat
Aplicación
immunohistochemistry
Anti-TPO (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
canine, guinea pig, horse, human, mouse, pig, rabbit, rat
Aplicación
western blot
Anti-TPO Antibody, clone 47, ,
Reactividad de especies
human
Aplicación
ELISA
radioimmunoassay
western blot
radioimmunoassay
western blot
Anti-Tpo Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
Small Molecule - Inhibitor
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Especie
Proteins
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Descripción
Especie
Thrombopoietin, TPO (Thrombopoietin, Mpl-ligand, MGDF) stimulates the proliferation & maturation of megakaryocytes & promotes increased circulating levels of platelets in vivo.,
Especie
human
esiRNA
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Especie