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Merck

TPM3

tropomyosin 3

Sinónimos:
CAPM1, CFTD, NEM1, OK/SW-cl.5, TM-5, TM3, TM30, TM30nm, TM5, TPMsk3, TRK, hscp30
Especie:
ID UniProtKB:
ID del gen:
  • Human(7170) Summary: This gene encodes a member of the tropomyosin family of actin-binding proteins. Tropomyosins are dimers of coiled-coil proteins that provide stability to actin filaments and regulate access of other actin-binding proteins. Mutations in this gene result in autosomal dominant nemaline myopathy and other muscle disorders. This locus is involved in translocations with other loci, including anaplastic lymphoma receptor tyrosine kinase (ALK) and neurotrophic tyrosine kinase receptor type 1 (NTRK1), which result in the formation of fusion proteins that act as oncogenes. There are numerous pseudogenes for this gene on different chromosomes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]
  • Mouse(59069) tropomyosin 3, gamma
  • Rat(117557) tropomyosin 3
  • Zebrafish(373076) tropomyosin 3
  • domestic cat(101099019) tropomyosin 3
  • dog(480137) tropomyosin 3
  • chicken(770103) tropomyosin 3
  • cow(497019) tropomyosin 3
  • sheep(101108973) tropomyosin 3
  • domestic guinea pig(100728267) tropomyosin 3
  • naked mole-rat(101701017) tropomyosin 3

Custom & Knockdown Gene Products

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-Tropomyosin Antibody, Chemicon®, from sheep,
Reactividad de especies
mouse, rat
Aplicación
immunocytochemistry
immunohistochemistry

western blot
Anti-Tropomyosin Antibody, 5NM1 and 5NM2, Chemicon®, from sheep,
Reactividad de especies
mouse, rat
Aplicación
immunocytochemistry
immunohistochemistry

western blot
Anti-Tropomyosin 3 Antibody, clone 2G10.2, ,
Reactividad de especies
human, mouse, rat
Aplicación
immunofluorescence
western blot

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human TPM3,
Especie
human
MISSION® esiRNA, targeting mouse Tpm3,
Especie
mouse