TP53
tumor protein p53
Sinónimos:
BCC7, LFS1, P53, TRP53
Especie:
Human TP53 (7157), Rat Tp53 (24842), Zebrafish tp53 (30590), Horse TP53 (100062044), domestic cat TP53 (493847), dog TP53 (403869), chicken TP53 (396200), cow TP53 (281542), sheep TP53 (443421), domestic guinea pig Tp53 (100379269) ...Más
ID UniProtKB:
ID del gen:
- Human(7157) Summary: This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277). [provided by RefSeq, Feb 2013]
- Rat(24842) tumor protein p53
- Zebrafish(30590) tumor protein p53
- Horse(100062044) tumor protein p53
- domestic cat(493847) tumor protein p53
- dog(403869) tumor protein p53
- chicken(396200) tumor protein p53
- cow(281542) tumor protein p53
- sheep(443421) tumor protein p53
- domestic guinea pig(100379269) tumor protein p53
- Domestic Rabbit(100009292) tumor protein p53
- naked mole-rat(101701769) tumor protein p53
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Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-p53 (wild type) Antibody, clone PAb1620, clone Pab1620, from mouse,
Reactividad de especies
human, mouse
Aplicación
immunohistochemistry
western blot
western blot
Anti-p53 Antibody, aa 211-220, clone240, clone PAb240, Chemicon®, from mouse,
Reactividad de especies
bovine, chicken, hamster, human, monkey, mouse, rat
Aplicación
immunohistochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-p53 (Ab-6) (Pantropic) Mouse mAb (DO-1), liquid, clone DO-1, Calbiochem®,
Reactividad de especies
feline, human
Aplicación
Anti-Acetyl-p53-K382 Antibody, clone 0, Rabbit Monoclonal, ,
Reactividad de especies
mouse
Aplicación
Anti-p53 (Ab-5) (Wild type) Mouse mAb (PAb1620), liquid, clone PAb1620, Calbiochem®,
Reactividad de especies
bovine, human, mouse, primate, rat
Aplicación
Small Molecule - Inhibitor
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Descripción
Especie
Proteins
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Descripción
Especie
p53 Protein, 10 µg, Full length, recombinant human p53. N-terminal c-Myc, 6His-tagged. For use in Enzyme Assays. Functions as a substrate in ubiquitination assays.,
Especie
p53 (1-81), mutant, GST tagged human, recombinant, expressed in E. coli, ≥80% (SDS-PAGE),
Especie
human
esiRNA
Referencia del producto
Descripción
Especie