TOP1
topoisomerase (DNA) I
Sinónimos:
TOPI
Especie:
Human TOP1 (7150), Mouse Top1 (21969), Rat Top1 (64550), fruit fly Top1 (32458), domestic cat TOP1 (101093174), dog TOP1 (477229), chicken TOP1 (396004), Zebrafish top1 (327179), domestic guinea pig Top1 (100716716), naked mole-rat Top1 (101704241) ...Más
ID UniProtKB:
ID del gen:
- Human(7150) Summary: This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus altering the topology of DNA. This gene is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22. [provided by RefSeq, Jul 2008]
- Mouse(21969) topoisomerase (DNA) I
- Rat(64550) topoisomerase (DNA) I
- fruit fly(32458) Topoisomerase 1
- domestic cat(101093174) topoisomerase (DNA) I
- dog(477229) topoisomerase (DNA) I
- chicken(396004) topoisomerase (DNA) I
- Zebrafish(327179) topoisomerase (DNA) I
- domestic guinea pig(100716716) topoisomerase (DNA) I
- naked mole-rat(101704241) topoisomerase (DNA) I
- cow(534799) topoisomerase (DNA) I
- sheep(101103086) topoisomerase (DNA) I
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Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anticuerpo anti-complejos covalentes topoisomerasa I-ADN, clon 1,1A, clone 1.1A, from mouse,
Reactividad de especies
human, mouse
Aplicación
ELISA
dot blot
flow cytometry
immunocytochemistry
dot blot
flow cytometry
immunocytochemistry
Anti-DNA topoisomerase I (TOP1) Antibody, clone 3D4W6, Rabbit Monoclonal, ,
Reactividad de especies
human, rat
Aplicación
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
immunohistochemistry
immunoprecipitation (IP)
western blot
Small Molecule - Inhibitor
Proteins
Referencia del producto
Descripción
Especie
Topo I (197-651) (core domain) human, recombinant, expressed in insect cells, ≥80% (SDS-PAGE),
Especie
human
Topo I (N1-197) (NTD) human, recombinant, expressed in insect cells, ≥85% (SDS-PAGE),
Especie
human
Topo I (C651-765) (C terminal domain) human, recombinant, expressed in insect cells, ≥80% (SDS-PAGE),
Especie
human
Topo I (Y723F) (mt Y723F) human, recombinant, expressed in insect cells, ≥80% (SDS-PAGE),
Especie
human