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Merck

TNFRSF11B

tumor necrosis factor receptor superfamily, member 11b

Sinónimos:
OCIF, OPG, TR1
Especie:
ID UniProtKB:
ID del gen:
  • Human(4982) Summary: The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined. [provided by RefSeq, Jul 2008]
  • Mouse(18383) tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)
  • Rat(25341) tumor necrosis factor receptor superfamily, member 11b
  • Zebrafish(407674) tumor necrosis factor receptor superfamily, member 11b
  • dog(482025) tumor necrosis factor receptor superfamily, member 11b
  • Horse(100065885) tumor necrosis factor receptor superfamily, member 11b
  • domestic cat(101096878) tumor necrosis factor receptor superfamily, member 11b
  • chicken(378803) tumor necrosis factor receptor superfamily, member 11b
  • domestic guinea pig(100715850) tumor necrosis factor receptor superfamily, member 11b
  • Domestic Rabbit(100348133) tumor necrosis factor receptor superfamily, member 11b
  • naked mole-rat(101709512) tumor necrosis factor receptor superfamily, member 11b
  • cow(523822) tumor necrosis factor receptor superfamily, member 11b
  • Goat(100860896) tumor necrosis factor receptor superfamily, member 11b

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-Osteoprotegerin/TNFRSF11B Antibody, from rabbit, purified by affinity chromatography,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
Anti-Tnfrsf11B Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human TNFRSF11B,
Especie
human