Saltar al contenido
Merck

TNFRSF10B

tumor necrosis factor receptor superfamily, member 10b

Sinónimos:
CD262, DR5, KILLER, KILLER/DR5, TRAIL-R2, TRAILR2, TRICK2, TRICK2A, TRICK2B, TRICKB, ZTNFR9
Especie:
ID UniProtKB:
ID del gen:
  • Human(8795) Summary: The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. [provided by RefSeq, Mar 2009]
  • Mouse(21933) tumor necrosis factor receptor superfamily, member 10b
  • Rat(364420) tumor necrosis factor receptor superfamily, member 10b
  • chicken(373904) tumor necrosis factor receptor superfamily, member 10b
  • naked mole-rat(101697353) tumor necrosis factor receptor superfamily, member 10b
  • cow(282533) tumor necrosis factor receptor superfamily, member 10b
  • cow(784541) tumor necrosis factor receptor superfamily, member 10b

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-TNFRSF10B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
Anti-DR5/CD262 Antibody, clone 1B19 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human, mouse
Aplicación
affinity binding assay
flow cytometry

immunocytochemistry

immunohistochemistry

western blot
Anti-DR5 Antibody, CT, Chemicon®, from rabbit,
Reactividad de especies
human
Aplicación
western blot

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human TNFRSF10B,
Especie
human
MISSION® esiRNA, targeting mouse Tnfrsf10b,
Especie
mouse