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Merck

TLR7

toll-like receptor 7

Sinónimos:
TLR7-like
Especie:
ID UniProtKB:
ID del gen:
  • Human(51284) Summary: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung, placenta, and spleen, and lies in close proximity to another family member, TLR8, on chromosome X. [provided by RefSeq, Jul 2008]
  • Mouse(170743) toll-like receptor 7
  • Rat(317468) toll-like receptor 7
  • cow(493686) toll-like receptor 7
  • sheep(554254) toll-like receptor 7
  • Goat(100860934) toll-like receptor 7
  • naked mole-rat(101705918) toll-like receptor 7
  • domestic guinea pig(100713329) toll-like receptor 7
  • Zebrafish(100534776) toll-like receptor 7
  • Horse(791248) toll-like receptor 7
  • domestic cat(493685) toll-like receptor 7
  • chicken(418638) toll-like receptor 7
  • dog(491743) toll-like receptor 7

Custom & Knockdown Gene Products

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Small Molecule - Agonist

Referencia del producto
Descripción
Especie
Imiquimod, ≥98% (HPLC), solid,
Especie
human
Imiquimod, United States Pharmacopeia (USP) Reference Standard,
Especie
human

Small Molecule - Antagonist

Referencia del producto
Descripción
Especie
Sulfato de hidroxicloroquina, ≥98% (HPLC), powder,
Especie
human
Hidroxicloroquina sulfate, United States Pharmacopeia (USP) Reference Standard,
Especie
human
Sulfato de hidroxicloroquina, British Pharmacopoeia (BP) Reference Standard,
Especie
human
Sulfato de hidroxicloroquina, British Pharmacopoeia (BP) Reference Standard,
Especie
human
2-((4-(7-Chloroquinolin-4-ylamino)pentyl)(ethyl)amino)ethanol, ,
Especie
human

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-TLR7 Mouse mAb (2C9), liquid, clone 2C9, Calbiochem®,
Reactividad de especies
human
Aplicación
Anti-TLR7 Antibody, clone 3G6S4, Rabbit Monoclonal, ,
Reactividad de especies
human
Aplicación
western blot

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting mouse Tlr7,
Especie
mouse
MISSION® esiRNA, targeting human TLR7,
Especie
human