THPO
thrombopoietin
Sinónimos:
MGDF, MKCSF, ML, MPLLG, THCYT1, TPO
Especie:
Human THPO (7066), Mouse Thpo (21832), Rat Thpo (81811), Zebrafish thpo (100189608), dog THPO (607489), domestic cat THPO (100302539), chicken THPO (414803), domestic guinea pig Thpo (100726592), naked mole-rat Thpo (101705058), cow THPO (538672)
ID UniProtKB:
ID del gen:
- Human(7066) Summary: Megakaryocytopoiesis is the cellular development process that leads to platelet production. The protein encoded by this gene is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene. Mutations in this gene are the cause of thrombocythemia 1. Alternate splicing results in multiple transcript variants of this gene.[provided by RefSeq, Jun 2012]
- Mouse(21832) thrombopoietin
- Rat(81811) thrombopoietin
- Zebrafish(100189608) thrombopoietin
- dog(607489) thrombopoietin
- domestic cat(100302539) thrombopoietin
- chicken(414803) thrombopoietin
- domestic guinea pig(100726592) thrombopoietin
- naked mole-rat(101705058) thrombopoietin
- cow(538672) thrombopoietin
- sheep(101119601) thrombopoietin
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