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Merck

TGFB1

transforming growth factor, beta 1

Sinónimos:
CED, DPD1, LAP, TGFB, TGFbeta
Especie:
ID UniProtKB:
ID del gen:
  • Human(7040) Summary: This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types. Many cells have TGFB receptors, and the protein positively and negatively regulates many other growth factors. The secreted protein is cleaved into a latency-associated peptide (LAP) and a mature TGFB1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGFB1 homodimer. The mature peptide may also form heterodimers with other TGFB family members. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease.[provided by RefSeq, Oct 2009]
  • Mouse(21803) transforming growth factor, beta 1
  • Rat(59086) transforming growth factor, beta 1
  • chicken(100873157) transforming growth factor beta 1
  • Horse(100033900) transforming growth factor, beta 1
  • dog(403998) transforming growth factor, beta 1
  • domestic cat(768263) transforming growth factor, beta 1
  • domestic guinea pig(100135628) transforming growth factor, beta 1
  • naked mole-rat(101704230) transforming growth factor, beta 1
  • Domestic Rabbit(100008645) transforming growth factor, beta 1
  • cow(282089) transforming growth factor, beta 1
  • sheep(443417) transforming growth factor, beta 1

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti- TGFB1 antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot
Anti-TGFB1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
Anti-TGF-β1 Antibody, clone 4E3 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
bovine, goat, horse, human, monkey, nonhuman primates, porcine, rat, sheep
Aplicación
flow cytometry
immunocytochemistry

immunohistochemistry

western blot

Proteins

Referencia del producto
Descripción
Especie
Factor de crecimiento transformante-β1 human, TGF-β1, recombinant, expressed in CHO cells, powder, suitable for cell culture,
Especie
human
Factor de crecimiento transformante-β1 human, TGF-β1, Xeno-free, recombinant, expressed in HEK 293 cells, suitable for cell culture,
Especie
human
Transforming Growth Factor-β1 Latency Associated Peptide human, ≥97% (SDS-PAGE), recombinant, expressed in Sf21 cells, lyophilized powder, suitable for cell culture,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human TGFB1,
Especie
human
MISSION® esiRNA, targeting mouse Tgfb1,
Especie
mouse