SPOP
speckle-type POZ protein
BTBD32, TEF2
Human SPOP (8405), Mouse Spop (20747), Rat Spop (287643), Zebrafish spop (100005514), chicken SPOP (425528), dog SPOP (480548), domestic cat SPOP (101094712), Horse SPOP (100056116), domestic guinea pig Spop (100713182), naked mole-rat Spop (101725604) ...Más
- Human(8405) Summary: This gene encodes a protein that may modulate the transcriptional repression activities of death-associated protein 6 (DAXX), which interacts with histone deacetylase, core histones, and other histone-associated proteins. In mouse, the encoded protein binds to the putative leucine zipper domain of macroH2A1.2, a variant H2A histone that is enriched on inactivated X chromosomes. The BTB/POZ domain of this protein has been shown in other proteins to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes. Alternative splicing of this gene results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
- Mouse(20747) speckle-type POZ protein
- Rat(287643) speckle-type POZ protein
- Zebrafish(100005514) speckle-type POZ protein
- chicken(425528) speckle-type POZ protein
- dog(480548) speckle-type POZ protein
- domestic cat(101094712) speckle-type POZ protein
- Horse(100056116) speckle-type POZ protein
- domestic guinea pig(100713182) speckle-type POZ protein
- naked mole-rat(101725604) speckle-type POZ protein
- Domestic Rabbit(100343929) speckle-type POZ protein
- cow(530618) speckle-type POZ protein
- sheep(101111300) speckle-type POZ protein
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