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Merck

SPOP

speckle-type POZ protein

Sinónimos:
BTBD32, TEF2
Especie:
ID UniProtKB:
ID del gen:
  • Human(8405) Summary: This gene encodes a protein that may modulate the transcriptional repression activities of death-associated protein 6 (DAXX), which interacts with histone deacetylase, core histones, and other histone-associated proteins. In mouse, the encoded protein binds to the putative leucine zipper domain of macroH2A1.2, a variant H2A histone that is enriched on inactivated X chromosomes. The BTB/POZ domain of this protein has been shown in other proteins to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes. Alternative splicing of this gene results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
  • Mouse(20747) speckle-type POZ protein
  • Rat(287643) speckle-type POZ protein
  • Zebrafish(100005514) speckle-type POZ protein
  • chicken(425528) speckle-type POZ protein
  • dog(480548) speckle-type POZ protein
  • domestic cat(101094712) speckle-type POZ protein
  • Horse(100056116) speckle-type POZ protein
  • domestic guinea pig(100713182) speckle-type POZ protein
  • naked mole-rat(101725604) speckle-type POZ protein
  • Domestic Rabbit(100343929) speckle-type POZ protein
  • cow(530618) speckle-type POZ protein
  • sheep(101111300) speckle-type POZ protein

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-SPOP Antibody, clone 2N8L8, Rabbit Monoclonal, ,
Reactividad de especies
human
Aplicación
western blot

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting mouse Spop,
Especie
mouse
MISSION® esiRNA, targeting human SPOP,
Especie
human