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Merck

SOX2

SRY (sex determining region Y)-box 2

Sinónimos:
ANOP3, MCOPS3
Especie:
ID UniProtKB:
ID del gen:
  • Human(6657) Summary: This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). [provided by RefSeq, Jul 2008]
  • Mouse(20674) SRY-box containing gene 2
  • Rat(499593) SRY (sex determining region Y)-box 2
  • Zebrafish(378723) SRY-box containing gene 2
  • Horse(100146979) SRY (sex determining region Y)-box 2
  • domestic cat(100379629) SRY (sex determining region Y)-box 2
  • dog(488092) SRY (sex determining region Y)-box 2
  • chicken(396105) SRY (sex determining region Y)-box 2
  • cow(784383) SRY (sex determining region Y)-box 2
  • Goat(100861576) SRY (sex determining region Y)-box 2
  • sheep(101110563) SRY (sex determining region Y)-box 2
  • domestic guinea pig(100714747) SRY (sex determining region Y)-box 2
  • naked mole-rat(101723266) SRY (sex determining region Y)-box 2

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anticuerpo anti-Sox2, Chemicon®, from rabbit,
Reactividad de especies
bovine, human, mouse, rat, rhesus macaque
Aplicación
immunocytochemistry
immunofluorescence

immunohistochemistry

western blot
Anti-Sox-2 Antibody, clone 1A2, ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human, mouse
Aplicación
immunocytochemistry
immunohistochemistry

western blot
Anti-Sox2, Alexa Fluor 488 Conjugate Antibody, from rabbit, ALEXA FLUOR 488,
Reactividad de especies
human, mouse
Aplicación
immunocytochemistry
Anti-Sox2 Mouse mAb (245610), lyophilized, clone 245610, Calbiochem®,
Reactividad de especies
human, mouse
Aplicación
Anti-SOX-2 Antibody, clone 6F1.2, Chemicon®, from mouse,
Reactividad de especies
human, mouse
Aplicación
immunocytochemistry
immunohistochemistry

western blot

Proteins

Referencia del producto
Descripción
Especie
Sox2 human, recombinant, expressed in E. coli, ≥95% (SDS-PAGE), ≥95% (HPLC), suitable for cell culture,
Especie
human
Sox2 TAT human, recombinant, expressed in E. coli, ≥95% (SDS-PAGE), ≥95% (HPLC), suitable for cell culture,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human SOX2,
Especie
human