SCN5A
sodium channel, voltage-gated, type V, alpha subunit
Sinónimos:
CDCD2, CMD1E, CMPD2, HB1, HB2, HBBD, HH1, ICCD, IVF, LQT3, Nav1.5, PFHB1, SSS1, VF1
Especie:
Human SCN5A (6331), Mouse Scn5a (20271), Rat Scn5a (25665), chicken SCN5A (395947), domestic cat SCN5A (101100994), Horse SCN5A (100034027), dog SCN5A (403497), domestic guinea pig Scn5a (100723340), naked mole-rat Scn5a (101710111), Domestic Rabbit SCN5A (100009516) ...Más
ID UniProtKB:
ID del gen:
- Human(6331) Summary: The protein encoded by this gene is an integral membrane protein and tetrodotoxin-resistant voltage-gated sodium channel subunit. This protein is found primarily in cardiac muscle and is responsible for the initial upstroke of the action potential in an electrocardiogram. Defects in this gene are a cause of long QT syndrome type 3 (LQT3), an autosomal dominant cardiac disease. Alternative splicing results in several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
- Mouse(20271) sodium channel, voltage-gated, type V, alpha
- Rat(25665) sodium channel, voltage-gated, type V, alpha subunit
- chicken(395947) sodium channel, voltage-gated, type V, alpha subunit
- domestic cat(101100994) sodium channel, voltage-gated, type V, alpha subunit
- Horse(100034027) sodium channel, voltage-gated, type V, alpha subunit
- dog(403497) sodium channel, voltage-gated, type V, alpha subunit
- domestic guinea pig(100723340) sodium channel, voltage-gated, type V, alpha subunit
- naked mole-rat(101710111) sodium channel, voltage-gated, type V, alpha subunit
- Domestic Rabbit(100009516) sodium channel, voltage-gated, type V, alpha subunit
- cow(282061) sodium channel, voltage-gated, type V, alpha subunit
- sheep(101111582) sodium channel, voltage-gated, type V, alpha subunit
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Antibodies
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Descripción
Reactividad de especies
Aplicación
Anti-Sodium Channel Nav1.5 Antibody, pain, Chemicon®, from rabbit,
Reactividad de especies
rat
Aplicación
western blot
Anti-SCN5A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
Anti-SCN5A (C-terminal) antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
bovine, canine, guinea pig, horse, human, mouse, rat
Aplicación
immunohistochemistry
western blot
western blot
Small Molecule - Blocker
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Especie
Flecainide for system suitability, European Pharmacopoeia (EP) Reference Standard,
Especie
human
esiRNA
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