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Merck

ROCK2

Rho-associated, coiled-coil containing protein kinase 2

Sinónimos:
ROCK-II
Especie:
ID UniProtKB:
ID del gen:
  • Human(9475) Summary: The protein encoded by this gene is a serine/threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c-fos serum response element. This protein, which is an isozyme of ROCK1 is a target for the small GTPase Rho. [provided by RefSeq, Jul 2008]
  • Mouse(19878) Rho-associated coiled-coil containing protein kinase 2
  • Rat(25537) Rho-associated coiled-coil containing protein kinase 2
  • chicken(374182) Rho-associated, coiled-coil containing protein kinase 2
  • dog(482970) Rho-associated, coiled-coil containing protein kinase 2
  • domestic cat(101094501) Rho-associated, coiled-coil containing protein kinase 2
  • cow(282041) Rho-associated, coiled-coil containing protein kinase 2
  • sheep(101103800) Rho-associated, coiled-coil containing protein kinase 2
  • sheep(100294663) Rho-associated, coiled-coil containing protein kinase 2
  • naked mole-rat(101724195) Rho-associated, coiled-coil containing protein kinase 2
  • domestic guinea pig(100713798) Rho-associated, coiled-coil containing protein kinase 2

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-ROCK2 Antibody, clone 1B20 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
canine, feline, horse, human, monkey, mouse, rat
Aplicación
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot
Anti-ROKα/ROCK-II Antibody, clone A9W4, rabbit monoclonal, culture supernatant, clone A9W4, from rabbit,
Reactividad de especies
bovine, human, mouse, rat
Aplicación
immunoprecipitation (IP)
western blot
Anti-ROCK2 Antibody, clone 8G3U2, Rabbit Monoclonal, ,
Reactividad de especies
human, rat
Aplicación
immunohistochemistry
western blot
Anti-ROCK2 Antibody, from rabbit, purified by affinity chromatography,
Reactividad de especies
mouse
Aplicación
immunohistochemistry
western blot

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
Y-27632 dihydrochloride, ≥98% (HPLC),
Especie
human
Adenina, ≥99%,
Especie
human, rat, mouse
Adenina, BioReagent, suitable for cell culture,
Especie
human, rat, mouse
Adenina, BioReagent, suitable for plant cell culture, ≥99%,
Especie
human, rat, mouse

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human ROCK2,
Especie
human