RNASEH2A
ribonuclease H2, subunit A
Sinónimos:
AGS4, JUNB, RNASEHI, RNHIA, RNHL
Especie:
Human RNASEH2A (10535), Mouse Rnaseh2a (69724), Rat Rnaseh2a (364974), Zebrafish rnaseh2a (393195), domestic cat RNASEH2A (101086121), dog RNASEH2A (484925), cow RNASEH2A (512830), sheep RNASEH2A (101105746), Goat RNASEH2A (100860936), domestic guinea pig Rnaseh2a (100715505)
ID UniProtKB:
ID del gen:
- Human(10535) Summary: The protein encoded by this gene is a component of the heterotrimeric type II ribonuclease H enzyme (RNAseH2). RNAseH2 is the major source of ribonuclease H activity in mammalian cells and endonucleolytically cleaves ribonucleotides. It is predicted to remove Okazaki fragment RNA primers during lagging strand DNA synthesis and to excise single ribonucleotides from DNA-DNA duplexes. Mutations in this gene cause Aicardi-Goutieres Syndrome (AGS), a an autosomal recessive neurological disorder characterized by progressive microcephaly and psychomotor retardation, intracranial calcifications, elevated levels of interferon-alpha and white blood cells in the cerebrospinal fluid.[provided by RefSeq, Aug 2009]
- Mouse(69724) ribonuclease H2, large subunit
- Rat(364974) ribonuclease H2, subunit A
- Zebrafish(393195) ribonuclease H2, subunit A
- domestic cat(101086121) ribonuclease H2, subunit A
- dog(484925) ribonuclease H2, subunit A
- cow(512830) ribonuclease H2, subunit A
- sheep(101105746) ribonuclease H2, subunit A
- Goat(100860936) ribonuclease H2, subunit A
- domestic guinea pig(100715505) ribonuclease H2, subunit A
- naked mole-rat(101714999) ribonuclease H2, subunit A
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